Chromatographic Separation of the Degradation Products of Pralidoxime Iodide (Pyridine-2-Aldoxime Methiodide)-Reference-Cited by-同舟云学术

Chromatographic Separation of the Degradation Products of Pralidoxime Iodide (Pyridine-2-Aldoxime Methiodide)

Published:1961-09 Issue:1 Volume:13 Page:370-373
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Ellin Robert I¹,Easterday David E¹

Affiliation:

1. Physiology Division, Directorate of Medical Research, U.S. Army Chemical Research and Development Laboratories, Army Chemical Center, Maryland

Abstract

Abstract A satisfactory method for the separation and identification of in vitro breakdown products of pralidoxime iodide (PAM; pyridine-2-aldoxime methiodide; 2-hydroxyiminomethyl-N-metnylpyridinium iodide) by paper chromatographic techniques is described

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/13/1/370/37754378/j.2042-7158.1961.tb11835.x.pdf

Reference5 articles.

1. Stability of Pyridine-2-aldoxime Methiodide. I. Mechanism of Breakdown in Aqueous Alkaline Solution

2. Identification of Alkaloids and Other Basic Drugs by Paper Partition Chromatography

3. Investigation of Methyl Pyridinium-2-aldoxime Salts

4. Analysis of Atropine and Its Hydrolytic Products by Filter Paper Chromatography**Physiology Division, Chemical Warfare Laboratories, Army Chemical Center, Maryland

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1. Pralidoxime Chloride;Analytical Profiles of Drug Substances;1988

2. A preformulation study on the kinetics of pralidoxime chloride in concentrated acidic solution;International Journal of Pharmaceutics;1987-11

3. Analysis of formulations containing pralidoxime mesylate by liquid chromatography;Journal of Chromatography A;1987-01

4. Degradation Pathway of Pralidoxime Chloride in Concentrated Acidic Solution;Journal of Pharmaceutical Sciences;1986-06

5. High-Performance Liquid Chromatographic Determination of Pralidoxime Chloride and Its Major Decomposition Products in Injectable Solutions;Journal of Pharmaceutical Sciences;1983-07