Affiliation:
1. Pharmacognosy Research Laboratory, Department of Pharmaceutical Chemistry, Sunderland Polytechnic, SRI 3SD, UK
Abstract
Abstract
Strychnine is separated from other alkaloids in nux vomica tincture in less than 6 min on a 12·5 cm Hypersil column using a mobile phase of methanol, 2 m ammonium hydroxide, m ammonium nitrate (27:2:1), uv detection at 254 nm. Quantitative estimation may be obtained by comparing peak area or height against an external standard (0·150% w/v strychnine base in 45% ethanol). The results obtained were comparable to those obtained by the BP method which takes 5 h.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
5 articles.
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