Affiliation:
1. Department of Pharmacology, University of Ife, Ile―Ife, Nigeria
Abstract
Abstract
The effect of diethylcarbamazine pretreatment on uterine contractility was investigated in both pregnant and nonpregnant rats. The pretreatment potentiated the uterine responses to oxytocin and acetylcholine, and enhanced the spontaneous uterine contraction of rats in oestrus or 17–20 days pregnant. This enhanced contraction was antagonized both in−vivo and in−vitro by indomethacin, suggesting the involvement of prostaglandins.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
4 articles.
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