Affiliation:
1. Research Laboratories, May and Baker Ltd., Dagenham, Essex, UK
Abstract
Abstract
The neuromuscular blocking activity of some 3- or 17-monoquaternary derivatives of 3β,17β-dipyrrolidin-1′-yl-5α-androstane has been examined in the cat. 3-Monoquaternary salts were, in general, more potent than the 17-monoquaternary salts. It was concluded that the presence of a quaternary group in position 3 is an important determinant of potency in this series of androstane derivatives.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
10 articles.
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