Affiliation:
1. Chemical Research Laboratories, The British Drug Houses Ltd., London, N.1
Abstract
Abstract
Work on sulphonamides as in vitro inhibitors of carbonic anhydrase has been extended by the preparation and assay of novel types. Although diphenylsulphonamides, p-alkoxycarbonylbenzene sulphonamides and 5-alkoxycarbonylamino-1:3:4-thiadiazole-2-sulphon-amides showed noteworthy activity in vitro, only the thiadiazole derivatives possessed diuretic activity in the rat.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
28 articles.
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