The Preparation and the Antibacterial and Antifungal Properties of Some Substituted Benzyl Alcohols-Reference-Cited by-同舟云学术

The Preparation and the Antibacterial and Antifungal Properties of Some Substituted Benzyl Alcohols

Published:1958-12 Issue:Supplement_1 Volume:10 Page:149T-159T
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Carter D V¹,Charlton P T¹,Fenton A H¹,Housley J R¹,Lessel B¹

Affiliation:

1. Pharmaceutical Development Department, Chemistry and Biology Divisions, Research Department, and Microbiology Division, Standards Department, Boots Pure Drug Co., Ltd., Nottingham

Abstract

Abstract A number of substituted benzyl alcohols have been prepared and together with some related, commercially available, compounds have been tested for antibacterial and antifungal properties. The most active inhibitory compound was 3:4:5-trichlorobenzyl alcohol followed by 4-chloro-3:5-dimethyl-, 3:4-dichloro- and 2:4-dichlorobenzyl alcohols, but saturated aqueus solutions of the last three compounds were more rapidly bactericidal. Pharmacological tests have shown that 2:4-dichlorobenzyl alcohol has low toxicity.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/10/Supplement_1/149T/37720264/j.2042-7158.1958.tb10394.x.pdf

Reference20 articles.

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