A High-Performance Liquid-Chromatographic Method for the Determination of in vitro Metabolites of Metyrapone
Author:
Affiliation:
1. Department of Pharmacy, University of Manchester M13 9PL, UK
2. Department of Pharmacy, Chelsea College(University of London), Manresa Road, London SW3 6LX, UK
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Link
http://academic.oup.com/jpp/article-pdf/31/Supplement_1/94P/37761769/j.2042-7158.1979.tb11642.x.pdf
Reference6 articles.
1. The binding of metyrapone to cytochrome P-450 and its inhibitory action on liver microsomal mixed-function oxidase reactions
2. A gas chromatographic method for the determination of metyrapone and its reduced derivative in plasma
3. Experiments on the metyrapone reducing microsomal enzyme system
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1. Determination of metyrapone and the enantiomers of its chiral metabolite metyrapol in human plasma and urine using coupled achiral-chiral liquid chromatography;Journal of Chromatography B: Biomedical Sciences and Applications;1995-03
2. Assay of metyrapone, metyrapol and the isomeric mono-N-oxides of metyrapone in biological fluids by high-performance liquid chromatography;Journal of Chromatography B: Biomedical Sciences and Applications;1991-02
3. Alteration of the inhibitory effect of metyrapone by reduction to metyrapol during the metabolism of methacetin in vivo in mice;Naunyn-Schmiedeberg's Archives of Pharmacology;1985-11
4. The metabolism of 3-benzoylpyridine;Xenobiotica;1983-01
5. Synthesis of N-oxide derivatives of metyrapone and their detection as in vitro metabolites;Journal of Pharmacy and Pharmacology;1981-09
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