Detection of Carbamazepine-induced Changes in Valproic Acid Relative Clearance in Man by Simple Pharmacokinetic Screening
Author:
Affiliation:
1. Division of Pharmaceutical Sciences, Graduate School, Kyushu University
2. Department of Hospital Pharmacy, Kyushu University Hospital, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-82, Japan
Abstract
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Link
http://academic.oup.com/jpp/article-pdf/49/8/751/37020256/j.2042-7158.1997.tb06106.x.pdf
Reference15 articles.
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2. Valproic acid dosage and plasma protein binding and clearance;Bowdle;Clin. Pharmacol. Ther.,1980
3. Comparison of steady-state pharmacokinetics of valproic acid in children between monotherapy and multiple anti-epileptic drug treatment;Chiba;J. Pediatr.,1985
4. Valproic acid pharmacokinetics in children. VI. Effects of age and antiepileptic drugs on protein binding and intrinsic clearance;Cloyd;Clin. Pharmacol. Ther.,1993
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