Infrared identification of pharmaceutically important steroids with particular reference to the occurrence of polymorphism-Reference-Cited by-同舟云学术

Infrared identification of pharmaceutically important steroids with particular reference to the occurrence of polymorphism

Published:1965-06 Issue:6 Volume:17 Page:329-340
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Mesley R J¹,Johnson C A²

Affiliation:

1. Laboratory of the Government Chemist, Cornwall House, Stamford Street, London, S.E.1

2. British Pharmacopoeia Commission, General Medical Council Office, 44, Hallam Street, London, W.1

Abstract

Abstract The infrared absorption spectra of steroids, when compared with the spectra of Authentic Specimens, provide a simple and complete means of identification, provided that the effects of polymorphism are precluded. Of 35 substances examined, 16 showed no evidence of polymorphism and a further twelve were sufficiently soluble to be examined in solution. Specific solvent treatments, details of which are given, may be necessary with the remaining seven substances if the spectra of the sample and of the Authentic Specimen are not identical when first examined.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/17/6/329/37680301/j.2042-7158.1965.tb07679.x.pdf

Reference29 articles.

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2. Solid State Anomalies in Infrared Spectroscopy

3. Digitalis X. The Infrared Absorption Spectra of Some Digitalis Glycosides and Aglycones * *Received August 1, 1959, from the School of Medicine, University of Maryland, Bultimore 1, Md.

4. X-Ray Diffraction Powder Date for Steroids

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