Affiliation:
1. Department of Pharmacology, Faculty of Pharmacy, University of Khartoum, Sudan
Abstract
Abstract
Cortisone, hydrocortisone and some of their Δ1- and fluorinated analogues have a pronounced diuretic effect in the rat; this is accompanied by increased urinary excretion of both Na+ and K+. Diuresis is maximal some 4 hr after oral administration, and in acute studies, the diuretic potency of some of the newer corticosteroids exceeds 100 times that of chlorothiazide.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
4 articles.
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