The compaction of some solid lubricant materials

Author:

Lewis C J1,Train D1

Affiliation:

1. Department of Pharmaceutics, School of Pharmacy, University of London, Brunswick Square, London, W.C.1

Abstract

Abstract Samples of −100 mesh powders of stearic acid, palmitic acid, sodium stearate, potassium stearate, lithium stearate, calcium stearate, magnesium stearate, zinc stearate, zinc oleate, boric acid and a synthetic wax, were compacted and the die reaction determined using a “moving-die” technique. The shear strength of the compacts measured in a punch penetration test, with the exception of boric acid and zinc stearate, was independent of the compaction pressure above 500 kg/cm2. Solid discs of stearic acid and palmitic acid possessed the same shear strength as the powder compacts; discs of synthetic wax and zinc stearate gave higher values than the corresponding powder compacts. Values of shear strength calculated from measurements of die reaction were higher than values obtained in the shear strength test, but show good agreement with the results calculated by other workers from sliding friction experiments. Shear strength values for compacts of boric acid and discs of synthetic wax, talc crystal, and graphite, indicate that these materials are unlikely to be such good lubricants as stearic acid or its salts.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Reference14 articles.

Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Pharmaceutical and Cosmetic Uses of Talc;Drug Development and Industrial Pharmacy;1990-01

2. Lubricants as a Formulation Factor Affecting In Vitro Properties of Double Compressed Tablets;Drug Development and Industrial Pharmacy;1988-01

3. Pharmaceutical tablet lubrication;International Journal of Pharmaceutics;1988-01

4. Glidants and Lubricant Properties of Several Types of Talcs;Drug Development and Industrial Pharmacy;1987-01

5. Equation relating to the Higuchi R-ratio of lubrication;International Journal of Pharmaceutics;1986-06

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3