Assay of nicotine in biological materials: sources of contamination and their elimination-Reference-Cited by-同舟云学术

Assay of nicotine in biological materials: sources of contamination and their elimination

Published:1980-09 Issue:1 Volume:32 Page:178-181
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Feyerabend C¹,Russell M A H²

Affiliation:

1. Poisons Unit, New Cross Hospital, London, SE14 5ER, UK

2. Addiction Research Unit, Institute of Psychiatry, Maudesley Hospital, London, SE5 8AF, UK

Abstract

Abstract A previous method for the measurement of nicotine in biological samples was subject to occasional interference from a contaminant which eluted simultaneously with the internal standard (quinoline). This has been rectified by substituting isoquinoline as the internal standard and modifying the operating conditions of gas chromatography. Other sources of contamination in nicotine assays such as the analytical reagents, the atmosphere and the sample itself are discussed in detail.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/32/1/178/37762398/j.2042-7158.1980.tb12885.x.pdf

Reference6 articles.

1. The determination of nicotine in human blood by gas-liquid chromatography

2. A modified procedure for the determination of nicotine in blood

3. A rapid gas-liquid chromatographic estimation of nicotine in biological fluids

4. Improved gas-chromatographic method and micro-extraction technique for the measurement of nicotine in biological fluids

5. Gas-liquid chromatographic determination of nicotine and cotinine in plasma.

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