The route of administration of imipramine as a factor affecting formation of its metabolite desipramine
Author:
Affiliation:
1. Department of Biochemistry, Institute of Pharmacology, Polish Academy of Sciences, 31–343 Kraków
2. Department of Physical Chemistry, School of Medicine, 31–512 Kraków, Poland
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Link
http://academic.oup.com/jpp/article-pdf/34/10/678/37622390/j.2042-7158.1982.tb04703.x.pdf
Reference8 articles.
1. Demethylation of imipramine in the rat as influenced by SKF 525-A and by different routes of administration
2. Intestinal absorption, demethylation, and enterohepatic circulation of imipramine
3. First-pass metabolism of imipramine in man
4. Blood and brain concentrations of imipramine, clomipramine and their monomethylated metabolites after oral and intramuscular administration in rats
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