Affiliation:
1. Department of Materia Medica and Therapeutics and Division of Experimental Pharmacology, Institute of Physiology, University of Glasgow
Abstract
Abstract
Orphenadrine possesses muscle-relaxant activity resembling that of tubocurarine in preparations of the hen, rat and frog. It antagonises suxamethonium-induced contracture in the hen but increases the duration of depression of the twitch height. The bearing of these findings upon the anti-Parkinson's activity and other uses of orphenadrine is discussed.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
12 articles.
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