Affiliation:
1. Department of Pharmaceutical Chemistry, School of Pharmacy, Trinity College, Dublin, Ireland
Abstract
Abstract
The values of the pseudo-first order hydrolysis rate constants in the pH range 1 to 10, and the pKa, were determined for cefazaflur in aqueous solution at 37°C and ionic strength 0·2 M. A fluorimetric assay, based on alkaline hydrolysis at 100°C, was also developed for this compound. The results are consistent with previously reported related properties of other monoprotic cephalosporins.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
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