Affiliation:
1. Department of Pharmacy, University of Manchester, Manchester 13, England
Abstract
Abstract
The absolute configuration of physostigmine has been established by correlating the configuration of its C-3a atom with that of the asymmetric carbon atom in (+)-3-ethyl-3-methoxycarbonyl-3-methylpropionic acid. Comparison of the optical rotatory dispersion spectra of physostigmine, Na-norphysostigmine, geneserine, physovenine and eseramine have shown that all five alkaloids have the same absolute configurations.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
15 articles.
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