Identification of a urinary metabolite of perazine as a piperazine-2,5-dione derivative-Reference-Cited by-同舟云学术

Identification of a urinary metabolite of perazine as a piperazine-2,5-dione derivative

Published:1969-12 Issue:12 Volume:21 Page:808-813
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Krauss Dietlinde¹²,Otting Walter¹²,Breyer Ursula¹²

Affiliation:

1. Organisch-chemisches Institut der Universität Heidelberg, Max-Planck-Institut für medizinische Forschung, 69 Heidelberg, Germany

2. Abteilung für Neurochemie, Universitäts-Nervenklinik, 665 Homburg/Saar, Germany

Abstract

Abstract A non-basic perazine metabolite has been isolated from the urine of schizophrenic patients ingesting perazine. Identification of this compound as 10-[3‘-(2“,5”-dioxo-4“-methyl-piperazinyl)-propyl]-phenothiazine sulphoxide was achieved using ultraviolet, infrared, nuclear magnetic resonance and mass spectroscopy.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/21/12/808/37713367/j.2042-7158.1969.tb08178.x.pdf

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2. Studies in mass spectrometry—XV

3. Urinary metabolites of 10-[3'-(4″-methyl-piperazinyl)-propyl]-phenothiazine (perazine) in psychiatric patients—I

4. Urinary metabolites of 10-[3?-(4?-methyl-piperazinyl)-propyl]-phenothiazine (perazine) in psychiatric patients

5. Diketopiperazine of Prolylhydroxyproline in Normal Human Urine.

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