The effect of Fluosol-DA and Hespan haemodilution on S-warfarin elimination in the rat-Reference-Cited by-同舟云学术

The effect of Fluosol-DA and Hespan haemodilution on S-warfarin elimination in the rat

Published:1990-09 Issue:9 Volume:42 Page:665-666
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Shrewsbury Robert P¹,Hong Donald D¹

Affiliation:

1. Division of Pharmaceutics, School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599-7360, USA

Abstract

Abstract Fluosol and Hespan haemodilution in rats did not change 5-warfarin elimination within 72 h although previous studies had indicated that Fluosol haemodilution caused an increased cytochrome P450b and P450c activity at 48 h. This study showed that the increased activity at that time was specific for those isoenzymes.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/42/9/665/37238461/j.2042-7158.1990.tb06630.x.pdf

Reference16 articles.

1. The use of single sample clearance estimates to probe hepatic drug metabolism in rats: II;Bachmann;Xenobiotica,1988

2. Phenobarbital type of induction of cytochrome P450 of liver microsomes by perfluorodecalin;Grishanova;Biokhimiya,1987

3. Comparative characterization of isolated forms of cytochrome P-450 inducible by phenobarbital and perfluorodecalin;Grishanova;Ibid.,1988

4. Effects of intravenous emulsified perfluorochemicals on hepatic cytochrome P-450;Huang;Biochem. Pharmacol.,1987

5. Warfarin as a probe of cytochromes P-450 function;Kaminsky;Drug Metab. Rev.,1989

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2. Acute Effects of Moderate Fluosol-DA Hemodilution on Hepatic Microsomal and Nonmicrosomal Metabolism in Rats;Biomaterials, Artificial Cells and Immobilization Biotechnology;1992-01