Mean residence time for drugs subject to reversible metabolism-Reference-Cited by-同舟云学术

Mean residence time for drugs subject to reversible metabolism

Published:1987-07 Issue:7 Volume:39 Page:565-567
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Aarons Leon¹

Affiliation:

1. Pharmacy Department, University of Manchester, Manchester M13 9PL, UK

Abstract

Abstract Conventional methods based on moment analysis lead to biased estimates of the mean residence time for drugs subject to reversible metabolism. A stochastic approach is described which enables unbiased estimation of the mean residence time.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/39/7/565/37541843/j.2042-7158.1987.tb03181.x.pdf

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