The Effect of a Sulphated Polysaccharide on the Acidity and Volume of Histamine-Stimulated Gastric Secretion in the Guinea-Pig-Reference-Cited by-同舟云学术

The Effect of a Sulphated Polysaccharide on the Acidity and Volume of Histamine-Stimulated Gastric Secretion in the Guinea-Pig

Published:1962-12 Issue:Supplement_1 Volume:14 Page:119T-121T
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Anderson W¹,Marcus R²,Watt J³

Affiliation:

1. Evans Medical Research Laboratories

2. Evans Medical Research Laboratories, Clatterbridge Hospital

3. Department of Pathology, University of Liverpool

Abstract

Abstract Degraded carrageenan administered in aqueous solution via an oesophageal tube to guinea-pigs twice daily and also freely available as drinking fluid, for 8 to 14 days, causes a 50 per cent reduction in the volume and acidity of histamine-stimulated gastric juice. This could be an important factor in the protection afforded by carrageenan against histamine-induced duodenal ulceration.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/14/Supplement_1/119T/37728242/j.2042-7158.1962.tb10545.x.pdf

Reference3 articles.

1. The Effect of a Sulphated Polysaccharide upon the Diffusion of Pepsin through Mucin

2. The Inhibition of Pepsin and Peptic Ulcers

Cited by 20 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. INHIBITORY EFFECT OF DEGRADED CARRAGEENAN ON THE FORMATION OF FASTING-INDUCED AVILLOUS LESIONS IN THE GUINEA-PIG DUODENUM;Acta Pathologica Microbiologica Scandinavica Section A Pathology;2009-08-15

2. Acidrine® in the Management of Gastritis and Duodenitis. A Double-Blind Placebo Controlled Clinical Trial;Journal of International Medical Research;1984-01

3. Drugs from the Sea;Science;1976-10-29

4. Effect of protease inhibitors on experimental peptic ulceration;The American Journal of Surgery;1970-02

5. Activation of pepsinogen by sulphated glycosaminoglycans: a possible role in peptic ulcerogenesis;Journal of Pharmacy and Pharmacology;1969-04