Ring-substituted β-methoxyphenethylamines: a new class of psychotomimetic agents active in man-Reference-Cited by-同舟云学术

Ring-substituted β-methoxyphenethylamines: a new class of psychotomimetic agents active in man

Published:1985-08 Issue:8 Volume:37 Page:575-577
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Lemaire D¹,Jacob P²,Shulgin A T³

Affiliation:

1. 101 Brownstone Drive, Reno, Nevada 89512, USA

2. 3787 Highland Road, Lafayette, California 95459, USA

3. 1483 Shulgin Road, Lafayette, California 94549, USA

Abstract

Abstract Four members of a new class of psychotomimetic agents have been synthesized and evaluated in man. These compounds, which incorporate a β-methoxy group onto a β-phenethylamine sidechain, are the first reported psychotomimetics which are structural analogues of the neurotransmitter noradrenaline. These substances are more potent than the corresponding phenethylamines (lacking a β-methoxy group) but less potent than the correspondingly substituted amphetamine derivatives.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/37/8/575/37533067/j.2042-7158.1985.tb03072.x.pdf

Reference9 articles.

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2. Substrates and inhibitors of dopamine-β-oxidase

3. Amphetamine analogs. II. Methylated phenethylamines

4. Sulfur analogs of psychotomimetic agents. 2. Analogs of (2,5-dimethoxy-4-methylphenyl)- and of (2,5-dimethoxy-4-ethylphenyl)isopropylamine

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