A selective potentiation by naloxone of L-dopa but not atropine suppression of oxotremorine-induced tremor in mice-Reference-Cited by-同舟云学术

A selective potentiation by naloxone of L-dopa but not atropine suppression of oxotremorine-induced tremor in mice

Published:1985-09 Issue:9 Volume:37 Page:673-674
ISSN:2042-7158
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Quock Raymond M¹,Scott Lucas T¹

Affiliation:

1. Division of Pharmacology, Department of Basic Sciences, Marquette University School of Dentistry, 604 N. 16th St, Milwaukee, Wisconsin 53233, USA

Abstract

Abstract Oxotremorine-induced tremor activity in mice was suppressed by pretreatment with either L-dopa or atropine. Additional pretreatment with the opiate receptor blocker naloxone significantly potentiated the antitremor effect of L-dopa but not that of atropine. These findings indicate a selectivity of drug interaction between naloxone and L-dopa.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/37/9/673/37533192/j.2042-7158.1985.tb05113.x.pdf

Reference12 articles.

1. Tremor Induced by Tremorine and Its Antagonism by Anti-Parkinson Drugs

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