The effect of temperature on the conductivity of gels and emulsions prepared from cetrimide and cetostearyl alcohol

Author:

Rowe R C1,Patel H K1

Affiliation:

1. ICI Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire SK10 2TG, UK

Abstract

Abstract The conductivity of gels and emulsions containing cetrimide, cetostearyl alcohol, liquid paraffin and water has been studied over the temperature range +35 to −10°C. All samples froze at temperatures below −5°C and exhibited hysteresis on rewarming to room temperature with an initial increase in conductivity up to 15°C followed by a decrease to 25°C. The amount of hysteresis was dependent on the cetostearyl alcohol content and appeared to be related to changes in the microstructure of the liquid crystalline network.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

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