Affiliation:
1. Area Renal Unit, Leicester General Hospital, Leicester LE5 4PW, UK
Abstract
Abstract
The effects of bezafibrate on hyperlipidaemia in experimental nephrotic syndrome in rats has been investigated. The treated group received bezafibrate l0 mg kg−1 p.o. daily. No significant differences in total serum cholesterol occurred, but a significant reduction in serum triglyceride (P < 0.005) and elevation in HDL cholesterol (P < 0.005) occurred. These findings may have implications for therapeutic intervention in severe hyperlipidaemia of the nephrotic syndrome in man.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
6 articles.
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