Antazoline Hydrochloride, Tripelennamine Hydrochloride and Locomotor Activity

Author:

Baird James A1,Boyd Eldon M1

Affiliation:

1. Department of Pharmacology, Queen's University, Kingston, Ontario, Canada

Abstract

Summary Tripelennamine hydrochloride and antazoline hydrochloride were administered orally and subcutaneously, in amounts of from 1 mg./kg. body weight up to lethal doses, to albino rats assembled in Wahmann vertically-revolving drums for the recording of locomotor activity. Tripelennamine hydrochloride had a statistically insignificant effect upon locomotor activity, while antazoline hydrochloride depressed locomotor activity.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

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