Effect of Lipophilicity of Ionisable Drugs on Deviations from Expected Ph-Partition Behaviour
Author:
Affiliation:
1. School of Pharmacy, Liverpool Polytechnic, Byrom Street, Liverpool L3 3AF, UK
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Link
http://academic.oup.com/jpp/article-pdf/30/Supplement_1/49P/37759583/j.2042-7158.1978.tb10756.x.pdf
Reference3 articles.
1. Partition coefficients and their uses
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1. Synthesis and quantitative structure-activity relationships of diclofenac analogs;Journal of Medicinal Chemistry;1990-09
2. The effect of salts on the distribution and solubility of an acidic drug;International Journal of Pharmaceutics;1989-02
3. Determination of the Partition Coefficients, Acid Dissociation Constants, and Intrinsic Solubility of Carbenoxolone;Journal of Pharmaceutical Sciences;1988-06
4. The Measurement of Partition Coefficients;Quantitative Structure-Activity Relationships;1988
5. Distribution Coefficients by Curve Fitting: Application to Ionogenic Nonsteroidal Antiinflammatory Drugs;Quantitative Structure-Activity Relationships;1986
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