Receptor interaction for the α-antagonist WB4101 (2-(N[2,6-dimethyoxyphenoxyethyl])amino-methyl-1,4-benzodioxane)
Author:
Affiliation:
1. Department of Pharmacology, School of Pharmacy, Liverpool Polytechnic, Byrom Street, Liverpool L3 3AF
2. Ward Blenkinsop & Co. Ltd., Widnes WA8 8NS, UK
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Link
http://academic.oup.com/jpp/article-pdf/30/1/259/37758075/j.2042-7158.1978.tb13221.x.pdf
Reference5 articles.
1. Adrenergic Blocking Properties of some New Benzodioxanes
2. Synthesis and pharmacological properties of a series of 2-substituted aminomethyl-1,4-benzodioxanes
3. Alpha-noradrenergic receptor binding in mammalian brain: Differential labeling of agonist and antagonist states
4. The α-adrenoceptor blocking effects of a new benzodioxane
5. pA, A NEW SCALE FOR THE MEASUREMENT OF DRUG ANTAGONISM
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1. 1,4-Benzodioxane, an evergreen, versatile scaffold in medicinal chemistry: A review of its recent applications in drug design;European Journal of Medicinal Chemistry;2020-08
2. Identification of WB4101, anα1-Adrenoceptor Antagonist, as a Sodium Channel Blocker;Molecular Pharmacology;2018-06-08
3. QSAR study for a novel series of ortho disubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101;European Journal of Medicinal Chemistry;2006-09
4. QSAR study for a novel series of ortho monosubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101;Bioorganic & Medicinal Chemistry;2005-04
5. Binding site analysis of full-length α1a adrenergic receptor using homology modeling and molecular docking;Biochemical and Biophysical Research Communications;2004-06
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