Synthesis of novel and functionally selective non-competitive muscarinic antagonists as chemical probes-Reference-Cited by-同舟云学术

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Synthesis of novel and functionally selective non-competitive muscarinic antagonists as chemical probes

Published:2017-07-17 Issue:1 Volume:91 Page:93-104
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Boulos John F.¹^ORCID,Jakubik Jan²,Boulos John M.³,Randakova Alena²,Momirov Jelena¹

Affiliation:

1. Department of Physical Sciences; Barry University; Miami Shores FL USA

2. Department of Neurochemistry; Institute of Physiology of the Academy of Sciences of the Czech Republic; Prague Czech Republic

3. Eshelman School of Pharmacy; University of North Carolina; Chapel Hill NC USA

Funder

Akademie Věd České Republiky

Grantová Agentura České Republiky

Barry University

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.13059/fullpdf

Reference32 articles.

1. M1 Muscarinic Agonists Target Major Hallmarks of Alzheimer’s Disease – The Pivotal Role of Brain M1 Receptors

2. Muscarinic acetylcholine receptors as CNS drug targets

3. Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse, and Parkinson’s Disease

4. Xanomeline and the Antipsychotic Potential of Muscarinic Receptor Subtype Selective Agonists

5. Xanomeline: A selective muscarinic agonist for the treatment of Alzheimer's disease

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1. Designing drugs and chemical probes with the dualsteric approach;Chemical Society Reviews;2023

2. Neurosteroids and steroid hormones are allosteric modulators of muscarinic receptors;Neuropharmacology;2021-11

3. Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors;Biochemical Pharmacology;2021-10

4. Guanidine Derivatives: How Simple Structural Modification of Histamine H3R Antagonists Has Led to the Discovery of Potent Muscarinic M2R/M4R Antagonists;ACS Chemical Neuroscience;2021-06-08

5. Agonist-Specific Conformations of the M2 Muscarinic Acetylcholine Receptor Assessed by Molecular Dynamics;Journal of Chemical Information and Modeling;2020-03-04

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