Controlled comparison evaluation of the soothing effect of 3 cosmetic products on skin discomfort induced by an irritant chemical agent (capsaicin)

Author:

Vitale Maria1,López Ana2ORCID,Truchuelo Maria Teresa3ORCID,Nobile Vincenzo4ORCID,Milani Massimo5ORCID,Gómez‐Sánchez María José1

Affiliation:

1. Medical Affairs Department Cantabria Labs Madrid Spain

2. R&D Department Cantabria Labs Madrid Spain

3. Vithas Nuestra Señora de América Hospital Madrid Spain

4. R&D Department Complife Italia S.r.l. Pavia Italy

5. Medical Department Cantabria Labs Difa Cooper Varese Italy

Abstract

AbstractBackgroundSensitive skin is a highly prevalent problem. The objective of the study was to assess whether the tested products are effective and safe in terms of improving the symptoms of sensitive skin.MethodsA clinical randomized split‐face study was carried out on 24 healthy female subjects. Three cosmetic combinations were tested versus vehicle: product A (Solía Thermal Spring Water–TSW–from Cantabria, Spain + diatom algae–P. tricornutum–extract), product B (Solía TSW + diatom algae extract + Annona cherimola Fruit Extract) and product C (Solía TSW + diatom algae extract + Annona cherimola Fruit Extract + niacinamide). Prior to each application of the study Product (A, B, or C)/vehicle, 10% of aqueous solution of capsaicin to induce skin irritation was applied, mimicking the symptoms of sensitive skin. Stinging and burning sensations were evaluated at different time points.ResultsAll three tested products A, B, and C showed to act better in calming the symptoms induced by capsaicin when compared to the vehicle.ConclusionsThe tested products would be an interesting option for treating stinging and burning sensations in sensitive skin patients.

Publisher

Wiley

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