A phase 2, open‐label study of single‐dose dupilumab in children aged 6 months to <6 years with severe uncontrolled atopic dermatitis: pharmacokinetics, safety and efficacy

Author:

Paller A.S.1,Siegfried E.C.2,Simpson E.L.3,Cork M.J.4,Lockshin B.5,Kosloski M.P.6,Kamal M.A.6,Davis J.D.6,Sun X.6,Pirozzi G.7,Graham N.M.H.6,Gadkari A.6,Eckert L.8ORCID,Ruddy M.6,Bansal A.6ORCID

Affiliation:

1. Northwestern University Feinberg School of Medicine Chicago IL USA

2. Saint Louis University and Cardinal Glennon Children's Hospital St. Louis MO USA

3. Oregon Health and Science University Portland OR USA

4. University of Sheffield Sheffield UK

5. Georgetown University Rockville MD USA

6. Regeneron Pharmaceuticals, Inc. Tarrytown NY USA

7. Sanofi Bridgewater NJ USA

8. Sanofi Chilly‐Mazarin France

Funder

Sanofi

Publisher

Wiley

Subject

Infectious Diseases,Dermatology

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1. Atopic dermatitis and IgE-mediated food allergy;Annals of Allergy, Asthma & Immunology;2024-09

2. Current and Emerging Biologics for Atopic Dermatitis;Immunology and Allergy Clinics of North America;2024-09

3. Drug Product Development and Case Studies for User Centric Pediatric Protein-Based Therapeutics;Journal of Pharmaceutical Sciences;2024-08

4. Chronic Spontaneous Urticaria;Immunology and Allergy Clinics of North America;2024-08

5. Dupilumab Reduces Urticaria Activity, Itch, and Hives in Patients with Chronic Spontaneous Urticaria Regardless of Baseline Serum Immunoglobulin E Levels;Dermatology and Therapy;2024-07-27

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