Congenital bullous syphilis in a newborn: A novel approach to diagnosis using immunohistochemical staining on a blister roof

Author:

Ekeh Odera1ORCID,Duffy Robert F.2,Feingold Anat34,Manders Steven M.2

Affiliation:

1. Cooper Medical School of Rowan University Camden New Jersey USA

2. Division of Dermatology Cooper University Health Care Camden New Jersey USA

3. Pediatric Infectious Disease, Cooper University Health Care Camden New Jersey USA

4. Department of Pediatrics Cooper University Health Care Camden New Jersey USA

Abstract

AbstractWe describe a rare presentation of congenital bullous syphilis in a premature neonate born with extensive skin desquamation. The newborn was noted to have diffuse erythema with widespread, superficial skin desquamation in addition to plantar bullae and erosions, and an absence of mucosal involvement. Immunohistochemical syphilis diagnostic staining was performed on a blister roof, highlighting a novel diagnostic approach for congenital bullous syphilis.

Publisher

Wiley

Subject

Dermatology,Pediatrics, Perinatology and Child Health

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