Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs-Reference-Cited by-同舟云学术

Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs

Published:2016-10 Issue:19 Volume:283 Page:3613-3625
ISSN:1742-464X
Container-title:The FEBS Journal
language:en
Short-container-title:FEBS J

Author:

Lee Sang Jae¹²^ORCID,Choi Jang-Sik³,Han Byeong-Gu¹,Kim Hyoun Sook¹,Song Ho-Juhn⁴,Lee Jaekyoo⁴,Nam Seungyoon⁵⁶,Goh Sung-Ho¹,Kim Jung-Ho³,Koh Jong Sung⁴,Lee Byung Il¹

Affiliation:

1. Research Institute; National Cancer Center; Goyang Gyeonggi Korea

2. The Research Institute of Pharmaceutical Sciences; College of Pharmacy; Seoul National University; Korea

3. Oscotec Inc.; Seongnam Gyeonggi Korea

4. Genosco; Cambridge MA USA

5. Department of Life Sciences; College of BioNano Technology; Gachon University; Sungnam Korea

6. Department of Genome Medicine and Science; Graduate School of Medicine; Gachon University; Incheon Korea

Funder

Ministry of Science, ICT and Future Planning

National Research Foundation of Korea

National Cancer Research Institute

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.13831/fullpdf

Reference43 articles.

1. Kinase inhibitors: the next generation of therapies in the treatment of rheumatoid arthritis;MacFarlane;Int J Rheum Dis,2014

2. Getting Syk: spleen tyrosine kinase as a therapeutic target;Geahlen;Trends Pharmacol Sci,2014

3. Discovery and development of spleen tyrosine kinase (SYK) inhibitors;Singh;J Med Chem,2012

4. Structural and biophysical characterization of the Syk activation switch;Gradler;J Mol Biol,2013

5. Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases;Latour;J Biol Chem,1996

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