Clozapine administration in clinical practice: once-daily versus divided dosing

Author:

Takeuchi H.123,Powell V.1,Geisler S.4,DeSanti M.1,Fervaha G.15,Agid O.125,Kane J. M.46,Remington G.1257

Affiliation:

1. Schizophrenia Division; Complex Mental Illness Program; Centre for Addiction and Mental Health; Toronto ON Canada

2. Department of Psychiatry; University of Toronto; Toronto ON Canada

3. Department of Neuropsychiatry; Keio University School of Medicine; Tokyo Japan

4. Department of Psychiatry; Zucker Hillside Hospital; Northwell Health; Glen Oaks NY USA

5. Institute of Medical Science; University of Toronto; Toronto Canada

6. Department of Psychiatry; Hofstra Northwell School of Medicine; Hempstead NY USA

7. Campbell Family Mental Health Research Institute; Centre for Addiction and Mental Health; Toronto ON Canada

Funder

Canadian Institutes of Health Research (CIHR)

Roche

Sepracor Inc.

Sunovion

Boehringer Ingelheim

Neurocrine Biosciences

Pfizer, Inc.

Medicure and Neurocrine Bioscience

Laboratorios Farmacéuticos ROVI

Synchroneuron

Centre for Addiction and Mental Health (CAMH) Foundation

Japanese Society of Clinical Neuropsychopharmacology

Astellas Foundation for Research on Metabolic Disorders

Dainippon Sumitomo Pharma

Novartis

Eli Lilly & Company U.S., Eli Lilly Canada, Janssen-Ortho (Johnson & Johnson), Lundbeck, Mylan Pharmaceuticals, Novartis, Sepracor Inc., and Sunovion

Bristol-Myers Squibb

Otsuka

Publisher

Wiley

Subject

Psychiatry and Mental health

Reference26 articles.

1. AGNP consensus guidelines for therapeutic drug monitoring in psychiatry: update 2011;Hiemke;Pharmacopsychiatry,2011

2. Novartis Pharmaceuticals Canada Clozaril Product Monograph http://www.novartis.ca/asknovartispharma/download.htm?res=clozaril_scrip_e.pdf%26resTitleId=685

3. Novartis Pharmaceuticals USA Clozaril Product Monograph http://www.us.novartis.com/product/pi/pdf/Clozaril.pdf

4. The Brief Psychiatric Rating Scale;Overall;Psychol Rep,1962

5. Remission in schizophrenia: proposed criteria and rationale for consensus;Andreasen;Am J Psychiatry,2005

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