Cinobufagin suppresses colorectal cancer angiogenesis by disrupting the endothelial mammalian target of rapamycin/hypoxia‐inducible factor 1α axis

Author:

Li Xiaowu123,Chen Chunhui2,Dai Yu2,Huang Chengzhi1,Han Qinrui2,Jing Linlin4,Ma Ye2,Xu Yihua2,Liu Yawei5,Zhao Liang5,Wang Junjiang1,Sun Xuegang26ORCID,Yao Xueqing12

Affiliation:

1. Department of Gastrointestinal SurgeryGuangdong Provincial People’s Hospital and Guangdong Academy of Medical Sciences Guangzhou Guangdong China

2. The Key Laboratory of Molecular BiologyState Administration of Traditional Chinese MedicineSchool of Traditional Chinese MedicineSouthern Medical University Guangzhou China

3. Department of General SurgeryThe First Affiliated Hospital & School of Clinical Medicine of Guangdong Pharmaceutical University Guangzhou China

4. Traditional Chinese Medicine Integrated HospitalSouthern Medical University Guangzhou China

5. Nanfang HospitalSouthern Medical University Guangzhou China

6. School of Basic Medical SciencesSouthern Medical University Guangzhou China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

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