Affiliation:
1. Institute for Anaesthesiology University Hospital Sint Radboud University of Nijmegen Nijmegen
Abstract
SUMMARYMuscle relaxants can be safely administered during anaesthesia, providing the basic pharmacodynamic and pharmacokinetic characteristics of the compounds together with the physiological status of the patient are known. In this review the pharmacodynamics and pharmacokinetics of the neuromuscular blocking agents are discussed and related to the physical health or disease state of groups of patients.