Affiliation:
1. Department of Medicine and Cardiology Unit University of the Wirwatersrand and the Johannesburg Hospital Johannesburg South Africa
Abstract
SUMMARY The aim of this review is to sort out from the huge amount of facts related to digoxin in the literature those pertinent to current clinical practice. Seven aspects of digoxin are discussed: its mechanism of action, therapeutic controversy, clinical efficacy, avoidance of toxicity, manifestations of toxicity, indications, and its use in coronary artery disease
Reference73 articles.
1. The sodium-potassium adenosine triphosphatase: pharmacological physiological and biochemical aspects;Schwartz A;Pharmacol Rev,1975
2. The role of Na+K+-ATPase in the inotropic action of digitalis;Akera T;Pharmacol Rev,1978
3. Digitalis
4. Zum Wirkungsmechanismus der Herzglykoside;Wilbrandt W;Schweiz Med Wochenschr,1965