Reducing Nav1.6 expression attenuates the pathogenesis of Alzheimer's disease by suppressing BACE1 transcription

Author:

Yuan De‐Juan1234,Yang Guang5,Wu Wei1,Li Qi‐Fa1,Xu De‐en234,Ntim Michael1,Jiang Chun‐Yan1,Liu Ji‐Chuan12,Zhang Yue1,Wang Ying‐Zi1,Zhu Dan‐Dan1,Kundu Supratik1,Li Ai‐Ping1,Xiao Zhi‐Cheng6,Ma Quan‐Hong23,Li Shao1ORCID

Affiliation:

1. Department of Physiology College of Basic Medical Sciences Liaoning Provincial Key Laboratory of Cerebral Diseases National‐Local Joint Engineering Research Center for Drug‐Research and Development (R&D) of Neurodegenerative Diseases Dalian Medical University Dalian China

2. Department of Neurology and Clinical Research Center of Neurological Disease The Second Affiliated Hospital of Soochow University Suzhou China

3. Jiangsu Key Laboratory of Neuropsychiatric Diseases Institute of Neuroscience Soochow University Suzhou China

4. The Affiliated Wuxi No. 2 People’s Hospital of Nanjing Medical University Wuxi China

5. Department of Thoracic Surgery Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China

6. Development and Stem Cells Program Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology Monash University Melbourne Victoria Australia

Publisher

Wiley

Subject

Cell Biology,Aging

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