Do directly acting antiviral agents for HCV increase the risk of hepatic decompensation and decline in renal function? Results from ERCHIVES

Author:

Butt A. A.1234,Ren Y.1,Marks K.4,Shaikh O. S.15,Sherman K. E.6,

Affiliation:

1. VA Pittsburgh Healthcare System; Pittsburgh PA USA

2. Weill Cornell Medical College; Doha Qatar

3. Weill Cornell Medical College; New York NY USA

4. Hamad Healthcare Quality Institute; Hamad Medical Corporation; Doha Qatar

5. University of Pittsburgh School of Medicine; Pittsburgh PA USA

6. University of Cincinnati; Cincinnati OH USA

Funder

AbbVie

Gilead Sciences

Anadys

Genentech

Merck

Novartis

Vertex

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Reference31 articles.

1. FDA FDA approves Viekira Pak to treat hepatitis C http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm427530.htm

2. FDA FDA Drug Safety Communication: FDA warns of serious liver injury risk with hepatitis C treatments Viekira Pak and Technivie http://www.fda.gov/Drugs/DrugSafety/ucm468634.htm

3. Hepatic decompensation likely attributable to simeprevir in patients with advanced cirrhosis;Stine;Dig Dis Sci,2015

4. Lactic acidosis in patients with hepatitis C virus cirrhosis and combined ribavirin/sofosbuvir treatment;Welker;J Hepatol,2016

5. Liver toxicity associated with sofosbuvir, an NS5A inhibitor and ribavirin use;Dyson;J Hepatol,2016

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