Inhibitor library screening identifies ispinesib as a new potential chemotherapeutic agent for pancreatic cancers
Author:
Affiliation:
1. Department of Hepatobiliary and Pancreatic Surgery Graduate School of Medicine Tokyo Medical and Dental University Tokyo Japan
2. Division of Molecular Oncology Graduate School of Medicine Tokyo Medical and Dental University Tokyo Japan
Funder
Japan Society for the Promotion of Science
Publisher
Wiley
Subject
Cancer Research,Oncology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/cas.15134
Reference39 articles.
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2. Cancer statistics, 2020
3. Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
4. Preoperative/Neoadjuvant Therapy in Pancreatic Cancer: A Systematic Review and Meta-analysis of Response and Resection Percentages
5. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.
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1. Design, Synthesis, and Evaluation of Biological Activity of Ferrocene‐Ispinesib Hybrids: Impact of a Ferrocenyl Group on the Antiproliferative and Kinesin Spindle Protein Inhibitory Activity;Chemistry – A European Journal;2023-07-31
2. Potent and Selective Benzothiazole-Based Antimitotics with Improved Water Solubility: Design, Synthesis, and Evaluation as Novel Anticancer Agents;Pharmaceutics;2023-06-09
3. Organometallic Ru, Os, Rh and Ir half-sandwich conjugates of ispinesib – impact of the organometallic group on the antimitotic activity;Dalton Transactions;2023
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