Incidence and risk factors for clinical neurodegenerative Langerhans cell histiocytosis: a longitudinal cohort study

Author:

Héritier Sébastien123ORCID,Barkaoui Mohamed-Aziz1,Miron Jean1,Thomas Caroline4,Moshous Despina5,Lambilliotte Anne6,Mazingue Françoise6,Kebaili Kamila7,Jeziorski Eric8,Plat Geneviève9,Aladjidi Nathalie10,Pacquement Hélène11,Galambrun Claire12,Brugières Laurence13ORCID,Leverger Guy314,Mansuy Ludovic15,Paillard Catherine16,Deville Anne17,Pagnier Anne18,Lutun Anne19,Gillibert-Yvert Marion20,Stephan Jean-Louis21,Cohen-Aubart Fleur22,Haroche Julien1422,Pellier Isabelle23,Millot Fréderic24,Gandemer Virginie25,Martin-Duverneuil Nadine26,Taly Valérie27,Hélias-Rodzewicz Zofia228,Emile Jean-François228,Hoang-Xuan Khe1429,Idbaih Ahmed29,Donadieu Jean123ORCID

Affiliation:

1. French Reference Centre for Langerhans Cell Histiocytosis; Trousseau Hospital; Paris France

2. EA4340; UVSQ; Université Paris-Saclay; Boulogne-Billancourt France

3. Department of Paediatric Haematology and Oncology; Trousseau Hospital; Assistance Publique-Hôpitaux de Paris; Paris France

4. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Nantes; Nantes France

5. Department of Paediatric Immunology, Haematology and Rheumatology; Necker Hospital; Assistance Publique-Hôpitaux de Paris; Paris France

6. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Lille; Lille France

7. Department of Paediatric Oncology; Institut d'Hémato-Oncologie Pediatrique; Lyon France

8. Department of Paediatrics; Hôpital Arnaud de Villeneuve; Centre Hospitalo-Universitaire de Montpellier; Montpellier France

9. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Toulouse; Toulouse France

10. Department of Paediatric Haematology and Oncology; CIC 1401 - INSERM CIC-P; Centre Hospitalo-Universitaire de Bordeaux; Bordeaux France

11. Paediatric, Adolescent and Young Adult Oncology Department; Institut Curie Medical Centre; Paris France

12. Department of Paediatric Haematology and Oncology; Assistance Publique - Hôpitaux de Marseille; Marseille France

13. Department of Paediatric and Adolescent Oncology; Institut Gustave Roussy; Villejuif France

14. Sorbonne Université; UPMC Univ Paris 6; Paris France

15. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Nancy; Vandœuvre-lès-Nancy France

16. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Strasbourg; Strasbourg France

17. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Nice; Nice France

18. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Grenoble; Grenoble France

19. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire d'Amiens; Amiens France

20. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Tours; Tours France

21. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Saint Etienne; Saint Etienne France

22. Department of Internal Medicine; French Reference Centre for Rare, Autoimmune and Systemic Diseases; Pitié -Salpêtrière Hospital; Assistance Publique-Hôpitaux de Paris; Paris France

23. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Angers; Angers France

24. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Poitiers; Poitiers France

25. Department of Paediatric Haematology and Oncology; Centre Hospitalo-Universitaire de Rennes; Rennes France

26. Department of Neuroradiology; Pitié -Salpêtrière Hospital; Assistance Publique-Hôpitaux de Paris; Paris France

27. INSERM; UMR-S1147; CNRS SNC5014; Paris Descartes University; Equipe labellisée Ligue Nationale contre le cancer; Paris France

28. Pathology Department; Ambroise Paré Hospital; Assistance Publique-Hôpitaux de Paris; Boulogne-Billancourt France

29. Department of Neurology; Pitié -Salpêtrière Hospital; Assistance Publique-Hôpitaux de Paris; Paris France

Funder

Conquer Cancer Foundation

Strike 3 Foundation

Publisher

Wiley

Subject

Hematology

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