A New Algorithm for Weekly Phenprocoumon Dose Variation in a Southern Brazilian Population: Role for CYP2C9, CYP3A4/5 and VKORC1 Genes Polymorphisms-Reference-Cited by-同舟云学术

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A New Algorithm for Weekly Phenprocoumon Dose Variation in a Southern Brazilian Population: Role for CYP2C9, CYP3A4/5 and VKORC1 Genes Polymorphisms

Published:2013-12-07 Issue:4 Volume:114 Page:323-329
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Botton Mariana R.¹,Viola Patrícia P.¹,Bandinelli Eliane¹,Leiria Tiago L. L.²,Rohde Luis E. P.³,Hutz Mara H.¹

Affiliation:

1. Genetics Department; Federal University of Rio Grande do Sul; Porto Alegre Brazil

2. Rio Grande do Sul Cardiology Institute - Cardiology University Foundation; Porto Alegre Brazil

3. Cardiology Division; Porto Alegre Clinics Hospital; Porto Alegre Brazil

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12172/fullpdf

Reference40 articles.

1. Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range;Hirsh;Chest,2001

2. Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin;Gage;Thromb Haemost,2004

3. Characteristics of anticoagulant therapy and comorbidity related to overanticoagulation;Penning-van Beest;Thromb Haemost,2001

4. Genetic determinants of acenocoumarol and phenprocoumon maintenance dose requirements;Cadamuro;Eur J Clin Pharmacol,2010

5. Prediction of phenprocoumon maintenance dose and phenprocoumon plasma concentration by genetic and non-genetic parameters;Geisen;Eur J Clin Pharmacol,2011

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1. Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients;Molecular Diagnosis & Therapy;2021-08-06

2. Pharmacogenomics research and clinical implementation in Brazil;Basic & Clinical Pharmacology & Toxicology;2019-01-24

3. Effects of age and genetic variations in VKORC1, CYP2C9 and CYP3A4 on the phenprocoumon dose in pediatric patients;Pharmacogenomics;2018-10

4. Problems in anticoagulation of a patient with antibiotic treatment for endocarditis: interaction of rifampicin and vitamin K antagonists;BMJ Case Reports;2018-02-12

5. Distribution of polymorphisms in the CYP2C9 gene and CYP2C19/CYP2C9 haplotypes among Venezuelan populations;Annals of Human Biology;2016-06-13

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