2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Increases Bilirubin Formation but Hampers Quantitative Hepatic Conversion of Biliverdin to Bilirubin in Rats with Wild-Type AH Receptor-Reference-Cited by-同舟云学术

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Increases Bilirubin Formation but Hampers Quantitative Hepatic Conversion of Biliverdin to Bilirubin in Rats with Wild-Type AH Receptor

Published:2014-02-15 Issue:6 Volume:114 Page:497-509
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Niittynen Marjo¹,Simanainen Ulla¹,Pohjanvirta Raimo²,Sankari Satu³,Tuomisto Jouni T.¹

Affiliation:

1. Department of Environmental Health; National Institute for Health and Welfare; Kuopio; Finland

2. Department of Food Hygiene and Environmental Health; Faculty of Veterinary Medicine; University of Helsinki; Helsinki Finland

3. Department of Equine and Small Animal Medicine; Faculty of Veterinary Medicine; University of Helsinki; Helsinki Finland

Funder

Academy of Finland

Emil Aaltonen Foundation

Finnish Cultural Foundation

The Graduate School in Environmental Health

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12191/fullpdf

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2. Essential role of the AH receptor in the dysfunction of heme metabolism induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin;Davies;Chem Res Toxicol,2008

3. Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models;Pohjanvirta;Pharmacol Rev,1994

4. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced accumulation of biliverdin and hepatic peliosis in rats;Niittynen;Toxicol Sci,2003