Sensitization of Hepatocellular Carcinoma Cells to Apo2L/TRAIL by a Novel Akt/NF-κB Signalling Inhibitor-Reference-Cited by-同舟云学术

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Sensitization of Hepatocellular Carcinoma Cells to Apo2L/TRAIL by a Novel Akt/NF-κB Signalling Inhibitor

Published:2014-02-08 Issue:6 Volume:114 Page:464-471
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Omar Hany A.¹²³,Arafa El-Shaimaa A.²,Maghrabi Ibrahim A.⁴,Weng Jing-Ru⁵

Affiliation:

1. Division of Medicinal Chemistry; College of Pharmacy; The Ohio State University; Columbus OH USA

2. Department of Pharmacology; Faculty of Pharmacy; Beni-Suef University; Beni-Suef Egypt

3. Department of Pharmacology; College of Pharmacy; University of Sharjah; Sharjah United Arab Emirates

4. Department of Clinical Pharmacy; College of Pharmacy; Taif University; Taif Saudi Arabia

5. Department of Biological Science and Technology; China Medical University; Taichung Taiwan

Funder

Taiwan Department of Health, China Medical University Hospital Cancer Research of Excellence

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12190/fullpdf

Reference37 articles.

1. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis;El-Serag;Gastroenterology,2007

2. Hepatocellular carcinoma: therapy and prevention;Blum;World J Gastroenterol,2005

3. Akt phosphorylation is a risk factor for early disease recurrence and poor prognosis in hepatocellular carcinoma;Nakanishi;Cancer,2005

4. Role of Rel/NF-kappaB transcription factors in apoptosis of human hepatocellular carcinoma cells;Chiao;Cancer,2002

5. Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma;Omar;Mol Pharmacol,2009

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