Successful live birth following a short course of glucocorticoid suppression in a patient with autoimmune polyglandular syndrome type 2 and premature ovarian insufficiency: A case report

Author:

Bradbury Rachel12ORCID,McLean Mark3,Smith Howard12

Affiliation:

1. Department of Endocrinology Westmead Hospital Sydney New South Wales Australia

2. Westmead Fertility Centre (Syd Uni) Sydney NSW Australia

3. Research and Education Network Building Westmead Hospital Sydney New South Wales Australia

Abstract

AbstractA 32‐year‐old nulliparous woman with premature ovarian insufficiency POI and autoimmune polyglandular syndrome type 2 (APS‐2), presented to our fertility center with a 2.5‐year history of amenorrhoea. Controlled ovarian hyperstimulation (COH), with high dose gonadotropins, failed to promote antral follicle growth. The patient was given a short, 4‐week course of 2 mg dexamethasone prior to a repeat COH cycle, which resulted in the retrieval of good oocyte numbers and eventual live birth from a thawed embryo transfer.

Publisher

Wiley

Subject

Obstetrics and Gynecology

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