Systemic Treatment with a miR-146a Mimic Suppresses Endotoxin Sensitivity and Partially Protects Mice from the Progression of Acute Graft-versus-Host Disease

Author:

Gartner J. G.12,Durston M. M.1,Booth S. A.34,Ellison C. A.12ORCID

Affiliation:

1. Department of Pathology; Max Rady College of Medicine; Rady Faculty of Health Sciences; University of Manitoba; Winnipeg MB Canada

2. Department of Immunology; Max Rady College of Medicine; Rady Faculty of Health Sciences; University of Manitoba; Winnipeg MB Canada

3. Molecular PathoBiology; National Microbiology Laboratory; Canadian Science Centre for Human and Animal Health; Public Health Agency of Canada; Winnipeg MB Canada

4. Department of Medical Microbiology and Infectious Diseases; Max Rady College of Medicine; Rady Faculty of Health Sciences; University of Manitoba; Winnipeg MB Canada

Funder

Research Manitoba

Publisher

Wiley

Subject

Immunology,General Medicine

Reference49 articles.

1. Pasquini MC Wang Z. Current use and outcome of hematopoietic stem cell transplantation: CIBMTR Summary Slides http://wwwcibmtrorg/ReferenceCenter/SlidesReports/SummarySlides/pages/indexaspx

2. Allosuppressor and allohelper T cells in acute and chronic graft-vs-host disease. V. F1 mice with secondary chronic GVHD contain F1-reactive allohelper but no allosuppressor T cells;Pals;J Exp Med,1984

3. Kinetics of Th1 and Th2 cytokine production during the early course of acute and chronic murine graft-versus-host disease. Regulatory role of donor CD8 + T cells;Rus;J Immunol,1995

4. Polarized type 2 alloreactive CD4+ and CD8+ donor T cells fail to induce experimental acute graft-versus-host disease;Krenger;J Immunol,1995

5. Murine graft-versus-host disease in an F1-hybrid model using IFN-gamma gene knockout donors;Ellison;J Immunol,1998

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