Clinical Outcomes of Isobar TTL System with Isthmic Bone Grafting and Pedicle Screw‐Vertebral Plate Hook with Direct Repair of Defect for Lumbar Spondylolysis: A Matched‐Pair Case Control Study

Author:

Li Qiujiang1ORCID,Hu Bowen1,Zhang Zhuang1,Kong Qingquan1,Gong Quan1,Liu Limin1,Yang Huiliang1,Wang Lei1,Song Yueming1ORCID

Affiliation:

1. Department of Orthopaedics, Orthopaedic Research Institute, West China Hospital Sichuan University Chengdu China

Abstract

ObjectiveAlthough direct isthmic repair, such as PSVPH, did not affect the mobility of the fixed segment and adjacent segment, it has a relatively low rate of isthmic fusion compared with conventional fusion. The Isobar TTL dynamic internal fixation system has been widely used in clinical practice and has achieved satisfactory clinical results. However, the use of the Isobar TTL system in combination with direct isthmic repair for lumbar spondylolysis has rarely been reported. The aim of this study was to compare the clinical and radiologic outcomes between patients who underwent Isobar TTL system and PSVPH with direct repair of defect for lumbar spondylolysis.MethodsStepwise propensity score matching (PSM) for age and sex were performed to keep comparable clinical data between groups in this retrospective and matched‐pair case control study. A total of 50 patients diagnosed with lumbar spondylolysis underwent surgical implantation of the Isobar TTL group (n = 25) or PSVPH group (n = 25) from June 2009 to June 2016. Clinical outcomes were assessed using the Oswestry disability index (ODI), and visual analog score (VAS). Radiographic evaluations included range of motion (ROM) and the disc heights of stabilized segment and adjacent segment, adjacent segment degeneration (ASD) and bony fusion. Three‐dimensional reconstruction of lumbar CT scan was obtained to evaluate bone fusion of the isthmic at final follow‐up. The independent Student's t test and chi‐square test were applied to compare the differences between groups.ResultsA total of 25 patients from TTL group were matched to 25 patients in PSVPH group for age, sex, body mass index (BMI), defect side, spondylolisthesis meyerding, and follow‐up duration. The intervertebral space height (IH) of stabilized segment at postoperative 1 week and final follow‐up in the TTL group was higher than those in the PSVPH group, respectively (P = 0.030; P = 0.013). The ROM of stabilized segment at final follow‐up in the TTL group was significantly lower than that in the PSVPH group (P < 0.001). The bony fusion rate at the final follow‐up was 88.0% (22/25 cages) in the TTL group and 80.0% (20/25 cages) in the PSVPH group. The ODI score at final follow‐up in the TTL group was significantly lower than that in the PSVPH group (P = 0.007).ConclusionOverall, our data suggest that the Isobar TTL system outcomes are comparable to those in the PSVPH, with a similar high bony fusion rate as PSVPH, especially its wider indications as a new surgery.

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Surgery

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