A structural variant at <i>ASIP</i> associated with the darkness of hair coat is found in multiple zebu cattle populations-Reference-Cited by-同舟云学术

A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations

Published:2023-06-14 Issue:4 Volume:54 Page:544-548
ISSN:0268-9146
Container-title:Animal Genetics
language:en
Short-container-title:Animal Genetics

Author:

Trigo Beatriz Batista¹²^ORCID,Alves Natália Fonseca¹²^ORCID,Milanesi Marco³⁴^ORCID,Garcia José Fernando¹²³⁵^ORCID,Terefe Endashaw⁶^ORCID,Hanotte Olivier⁶^ORCID,Tijjani Abdulfatai⁶⁷^ORCID,Utsunomiya Yuri Tani¹^ORCID

Affiliation:

1. Department of Production and Animal Health, School of Veterinary Medicine of Araçatuba São Paulo State University (UNESP) Araçatuba Brazil

2. International Atomic Energy Agency (IAEA) Collaborating Centre on Animal Genomics and Bioinformatics Araçatuba Brazil

3. AgroPartners Consulting Araçatuba Brazil

4. Department for Innovation in Biological, Agro‐Food and Forest Systems (DIBAF) University of Tuscia Viterbo Italy

5. Department of Preventive Veterinary Medicine and Animal Reproduction, School of Agricultural and Veterinarian Sciences São Paulo State University (UNESP) Jaboticabal Brazil

6. International Livestock Research Institute (ILRI) Addis Ababa Ethiopia

7. The Jackson Laboratory Bar Habor Maine USA

Abstract

AbstractA structural variant (SV) in the agouti signaling protein gene (ASIP), namely ASIP‐SV1, has been found to strongly correlate with the darkness of hair coat in specific regions of the body of bulls from the zebu (Bos indicus) Nellore breed. Here we visually analyzed the whole‐genome sequence of zebu and taurine (Bos taurus) cattle to elucidate the extent of spread of ASIP‐SV1 in different cattle populations. Of 216 sequences analyzed, 63 zebu (45.9%) and five taurine (6.3%) animals had at least one copy of ASIP‐SV1. Four of the taurine animals presenting the SV were Romagnola cattle, a breed with history of zebu introgression. The remaining taurine animal was a Simmental, a breed frequently used in crossbreeding. These data provide evidence that ASIP‐SV1 is commonly found in zebu populations, in addition to taurine animals with zebu admixture.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Wiley

Subject

Genetics,Animal Science and Zoology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/age.13333

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