Red cell distribution width to albumin ratio predicts treatment failure in peritoneal dialysis‐associated peritonitis

Author:

He Yujian1ORCID,Xiao Fei1,Luo Qingyun1,Liao Jinlan1,Huang Huie1,He Yan1,Gao Min1,Liao Yumei1,Xiong Zibo1ORCID

Affiliation:

1. Renal Division Peking University Shenzhen Hospital (PKU‐Shenzhen Clinical Institute of Shantou University Medical College, PKU‐Shenzhen Clinical Institute of Shenzhen University Medical College) Shenzhen China

Abstract

AbstractBackgroundThis study aims to investigate the potential correlation between baseline red cell distribution width (RDW) to albumin ratio (RAR) levels and treatment failure in peritoneal dialysis‐associated peritonitis (PDAP) patients.MethodsA retrospective single‐center study was conducted on 286 PDAP patients. Logistic regression and generalized estimation equation (GEE) analyses were employed to assess the relationship between RAR and treatment failure.ResultsRAR emerged as a robust predictor of treatment failure in PDAP patients. Elevated RAR levels were associated with an increased risk of treatment failure, exhibiting a linear relationship. Even after adjusting for demographic and clinical variables, this association remained statistically significant. ROC analysis revealed that RAR outperformed RDW and albumin individually in predicting PDAP prognosis.ConclusionThis study highlights RAR as a superior prognostic marker for treatment failure in PDAP patients, offering new insights into risk assessment and management strategies for this challenging condition.

Publisher

Wiley

Subject

Nephrology,Hematology

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