Affiliation:
1. Nephrology Department University of Medicine and Pharmacy "Carol Davila" Bucharest Romania
2. Nephrology Department “Dr. Carol Davila” Teaching Hospital of Nephrology Bucharest Romania
Abstract
AbstractIntroductionThis retrospective study examined the relationship between the Glasgow Prognostic Score (GPS) at hemodialysis (HD) initiation and overall/cardiovascular mortality.MethodsA total of 264 patients starting HD between 2014 and 2015 at a single center were studied. Follow‐up persisted until therapy change, death, or study end (December 31, 2021), with a median of 6.8 years.ResultsPatients with a higher GPS more frequently had emergent HD initiation and showed increased eGFR at initiation. During follow‐up, 60% of patients died, with cardiovascular disease being the leading cause. Univariate analysis revealed a significant difference in median survival time across GPS classes. Cox proportional hazard models confirmed a significant association between GPS and mortality.ConclusionsWe report a significant association between GPS at HD initiation and mortality. GPS may prove useful as a prognostic tool for identifying high‐risk patients, underscoring the need for future research to validate these findings and explore the potential of GPS‐based interventions.