COVID‐19 is more lethal in hemodialysis chronic kidney disease patients with low physical capacity

Author:

Orcy Rafael B.12ORCID,Bluhm Caroline C.1,Ribeiro Larissa R.3,Sosa Priscila M.4,Correa Bianca D.4,Barcellos Franklin C.5,Böhlke Maristela35ORCID

Affiliation:

1. Postgraduate Programme in Physical Education Federal University of Pelotas Pelotas Brazil

2. Multicenter Postgraduate Programme in Physiological Sciences Federal University of Pelota Pelotas Brazil

3. Postgraduate Programme in Health and Behaviour Catholic University of Pelotas Pelotas Brazil

4. Higher School of Physical Education and Physiotherapy Federal University of Pelotas Pelotas Brazil

5. Dialysis and Kidney Transplantation Unit São Francisco de Paula University Hospital Pelotas Brazil

Abstract

AbstractIntroductionThe mortality rate in patients on maintenance hemodialysis (HD) is high and is associated with low functional capacity (FC). We analyzed the association of FC and COVID‐19 lethality among HD patients.MethodsA cohort study that included evaluations of FC in patients on HD was underway, and the association between FC and lethality was included as an ad‐hoc outcome.ResultsOne hundred and twelve patients were submitted to a physical, 31 patients contracted symptomatic COVID‐19, 20 recovered and 11 died (lethality rate of 35.5%). There was a difference between survivors and non‐survivors on six‐minutes‐walking‐test (6MWT) 386.1 ± 112.8 versus 296.9 ± 103.3 meters (p = 0.04), 30 s sit‐to‐stand test (30CST) score 11.7 ± 3.1 versus 7.7 ± 4.1 (p = 0.006), and timed up and go test (TUG) 9.4 versus 13.6 s (p = 0.009). There was also an association between percentages of predicted 6MWT, 30CST, and TUG with COVID‐19 lethality.ConclusionPatients on maintenance HD with poorer physical performance presented the worst prognosis from COVID‐19 pandemic.

Publisher

Wiley

Subject

Nephrology,Hematology

Reference36 articles.

1. Centers for Disease Control and Prevention.COVID‐19 people of any age with underlying medical conditions.2021Available from:https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-with-medical-conditions.html

2. MO819RISK FACTORS FOR COVID-19 MORTALITY IN HEMODIALYSIS PATIENTS

3. Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: a study in 48 440 adult patients

4. Physical function was related to mortality in patients with chronic kidney disease and dialysis

5. Association of CKD With Disability in the United States

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